The project will be focussed on the elucidation of crystal structures of constituent enzymes of the MEP pathway from pathogenic organisms (Pseudomonas aeruginosa, Plasmodium falciparum, Mycobacterium tuberculosis, Escherichia coli). Over the past decades, structural biologists have extensively studied the MEP pathway enzymes. Nevertheless, important gaps remain to be addressed. By adopting an extensive structural-genomics approach … Continue reading WP 1: STRUCTURAL BIOLOGY OF THE ENZYME OF THE PATHWAY